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PubMed COVID-19 Clinical Care

3031 - 3040 of 5280 results found

Tau protein aggregation associated with SARS-CoV-2 main protease

Date
Monday, August 21, 2023 - 4:00 AM
Description
The primary function of virus proteases is the proteolytic processing of the viral polyprotein. These enzymes can also cleave host cell proteins, which is important for viral pathogenicity, modulation of cellular processes, viral replication, the

The microbiome in post-acute infection syndrome (PAIS)

Date
Monday, August 21, 2023 - 4:00 AM
Description
Post-Acute Infection Syndrome (PAIS) is a relatively new medical terminology that represents prolonged sequelae symptoms after acute infection by numerous pathogenic agents. Imposing a substantial public health burden worldwide, PASC (post-acute

The immunology of PF4 polyanion interactions

Date
Monday, August 21, 2023 - 4:00 AM
Description
PURPOSE OF REVIEW: Platelet factor 4 (PF4, CXCL4), the most abundant α-granule platelet-specific chemokine, forms tetramers with an equatorial ring of high positive charge that bind to a wide range of polyanions, after which it changes conformation

The facilitators and barriers to improving functional activity and wellbeing in people with dementia: a qualitative study from the process evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED)

Date
Monday, August 21, 2023 - 4:00 AM
Description
CONCLUSIONS: Self-directed interventions may not be appropriate in the context of dementia, even in the mild stages of the condition. Dementia-specific factors affected outcomes including caregiver support, rapport with therapists, availability of