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PubMed COVID-19 Clinical Care

29551 - 29560 of 50647 results found

Graphical Learning and Causal Inference for Drug Repurposing

Date
Monday, August 14, 2023 - 4:00 AM
Description
Gene expression profiles that connect drug perturbations, disease gene expression signatures, and clinical data are important for discovering potential drug repurposing indications. However, the current approach to gene expression reversal has

Biophysical principles predict fitness of SARS-CoV-2 variants

Date
Monday, August 14, 2023 - 4:00 AM
Description
SARS-CoV-2 employs its spike protein's receptor binding domain (RBD) to enter host cells. The RBD is constantly subjected to immune responses, while requiring efficient binding to host cell receptors for successful infection. However, understanding

Characterizing provider-led adaptations to mobile phone delivery of the Adolescent Transition Package (ATP) in Kenya using the Framework for Reporting Adaptations and Modifications to Evidence-based Implementation Strategies (FRAME-IS): a mixed methods...

Date
Monday, August 14, 2023 - 4:00 AM
Description
CONCLUSION: Adaptation of phone delivery was a feasible and effective way of addressing challenges with continuity of care for YLH during the COVID-19 pandemic. Adaptations were primarily context adaptions. While FRAME-IS was apt for characterizing